7/1/2023 0 Comments Vertis freeze dryer3 of the study paper, annealing at 166K, slightly above the Tg=163 K, increased the oxidation rate which could indicate increased instability. The glassy sample was prepared by “freezing” of liquid 2-methylpentanol-2 in liquid nitrogen followed by gamma-irradiation. 195 (1995) 305-311, the effect of annealing slightly above Tg on oxidation of free radicals in 2-methylpentanol-2 was reported. Vasenkov, et, al., “The influence of deep traps for gas molecules on oxygen transport in the glass of 2-methylpentanol-2”, Chem. The literature discloses annealing as one way to stabilize amorphous materials. Thus, there has been ongoing investigation to find ways to stabilize pharmaceutical compositions. While freeze-drying has become a standard method utilized for the stabilization of many drug substances in the solid state, many freeze-dried materials undergo chemical degradation during storage. The solution contains an accelerant excipient to enhance the rate of solvent sublimation. The method comprises the steps of freezing the solution to a temperature at or below the lower of its eutectic temperature or its glass transition temperature, and in a first drying stage, removing at least a portion of the solvent by sublimation. WO99/30688 describes a method of lyophilizing a solution. Depending on its chemical composition and conditions of freeze-drying, the dried product may be wholly or partially disordered or amorphous. Freeze-drying typically consists of three stages: 1) concentration of the product by freezing (removal of liquid water) 2) sublimation of the ice so formed and 3) removal from the product of residual unfrozen water by diffusion/desorption/evaporation. Freeze-drying may be accomplished by any method known in the art. Such changes can include chemical modifications and phase transformations which may affect various pharmaceutical properties such as stability and bioavailability of drug.įreeze-drying or lyophilization is one well-known method used to stabilize drug substances. BACKGROUND OF THE INVENTIONĪn understanding of the physical and chemical processes which can lead to unwanted changes in amorphous or other disordered state systems during prolonged storage is a fundamental concern to pharmaceutical scientists. In particular, the present invention relates to a method of increasing the stability of pharmaceutical compositions containing cefovecin sodium salt which is in an amorphous or other disordered state. The present invention relates to a method of stabilizing pharmaceutical compositions.
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7/1/2023 0 Comments Osx free exif editorPhotos EXIF Editor makes it possible to edit EXIF information of thousands of photos in just no time. This image EXIF editor could be a little tedious for a new users, but has a wide variety of features to make use of. It is a small and portable software, which you do not need to install. Quick EXIF Editor is a freeware to edit EXIF data. Here is the list of best exif viewers to edit and remove exif data on Windows and Mac. 10 Best Exif Data Editor & Remover For Mac And Windows They will help you to change or remove your device identity, time, date and location of images. Fortunately, you can edit Exif data with tools which are called as Exif Editor or Exif Viewer. If you’re concerned about your privacy, then you don’t want your friends to know when and where the picture was taken. When you are sharing your images with your friends or uploading them on social media then the Exif data is also shared with others. The information is attached to the images is called EXIF data. To get the perfect shot we use high tech gadgets and professional cameras which also stores the whole information into the image such as device identity, time, date, and location. Uploading photos and videos on social media platforms has become a status symbol nowadays. Here are a few reasons which make it a MUST HAVE photo metadata editing tool for your Mac. Photos EXIF Editor makes it possible to edit EXIF information of thousands of photos on your Mac in no time at all. 6/30/2023 0 Comments Blue cool katanaQuality service and professional assistance is provided when you shop with Truekatana, Start the best shopping experience you�ll ever have, right here. Free 3D katana models for download, files in 3ds, max, c4d, maya, blend, obj, fbx with low poly, animated, rigged, game, and VR options. Looking for something more? Truekatana carries many cool blue sword related products, including blue katana sword, blue steel katana, blue dragon katana. With the lowest prices online, free shipping and local collection options, You can make an even bigger saving. Find out the best quality blue katanas hand forged and functional. Shipping 269.00 USD Add to Cart Handmade Japanese Samurai Sword 1045 Carbon Steel With Blue Scabbard Free U.S. Think how jealous you�re friends will be when you tell them you got your cool blue sword on TrueKatana. 249.00 USD Add to Cart Handmade Japanese Samurai Sword T10 Folded Clay Tempered Steel 1 Reviews Free U.S. But you may have to act fast as these top cool blue sword is set to become one of the most sought-after best-sellers in no time. Custom Katana Build your custom Katana from the options below, We offer the largest selection of blade modifications for your Custom Katana, and other samurai swords. Įvery day you�ll find new, online-only offers, discounts and the opportunity to save even more by collecting coupons. Customize Your Own Cool Katana 0.00 Customized Katana AJ 688.00 Folded Steel From 445.00 Gilt Silver Tsuba From 88.00 Habaki From 13. Blade has stainless steel, gold carbon steel, t10 tool steel, red blade, hand grinding, purple blade and more. Handle(tsuka) has blue cord handle, orange cord handle, black cord handle, wood handle. We also know that personalization is in the details, so we offer many different cool blue sword derivative series like scabbard(saya) has red wooden scabbard, yellow scabbard, cheetah style scabbard, fishskin scabbard etc. TrueKatana carries wide variety of products, If you are interested in cool blue sword, So you can compare and shop! Short katana, handmade wakizashi sword pattern steel with bl. Handmade pattern steel full tang real japanese wakizashi swo. Handmade shirasaya wakizashi sword t10 carbon steel without. We believe in helping you find the product that is right for you. Handmade shirasaya wakizashi swords without tsuba with rosew. Popular cool blue sword of good quality and at affordable prices you can buy on TrueKatanaOur team has more than 30 years of experience in making swords, and your order will be fully handmade by seasoned sword-smiths using advanced techniques honed over centurie. 6/30/2023 0 Comments Spike hair menNo TOMT posts looking for Warez or requests for anything illegal. This rule will generally be handled on a case by case basis. Actors/actresses and historical figures who are not common knowledge within the public domain are off limits. If there is a similar song to the one you are looking for, provide a link to that. This applies even if the singer doo-doo-doo’s the melody in the song. Describing musical notes as text without including a vocaroo or other playable link will get your post removed - this includes “do doo dooo” or other attempts at written music notation, including Solfège. Make it easy for people to help you by recording a vocaroo or providing an online synthesiser recording of your music. Wait one week before reposting a question (Please link to your old posts to rule out previous suggestions) People are interested in what has been asked for, what has been suggested, and want to see what has been found. When what you’re looking for is found, reply Solved! in reply to the first (oldest) comment that gave you the answer.ĭo not delete your answer after it has been acknowledged. Reply “Solved!” to the first correct answer If you have replied with the same thing as someone else did earlier, you should delete your comment.Ĥ. The OP does not need to be overwhelmed with multiple suggestions of the same thing. Do not repeat something already suggested. Do not use URL shorteners, Tumblr, or partner links, these are all automatically removed.ģ. Include a description of what you are linking to in case the link breaks. No arbitrary link titles (How to answer including a link) Be civil and respectful to each other.Īct in good faith on this subreddit, posts and answers. You can also modify the search by adding keywords to the search bar.īEFORE POSTING HERE, PLEASE READ THIS GUIDE on how to find what you need using regular means! Subreddit Rulesġ. NOTE: To mark your submissions solved reply "Solved!" to the oldest comment with the answer. New to reddit? Check out this tutorial on how to post successfully to this sub. Read the rules and suggestions for tips on how to get the most out of TOMT. Submit a Question Submit NSFW Join TOMT Discord for live discussion Please read the FAQ before posting!Ĭan't remember the name of that movie you saw when you were a kid? Or the name of that video game you had for Game Gear? This is the place to get help. Reply Solved! to the comment that answers your post. Since downloading them I am now able to access the. That’s what I was thinking as well, so I downloaded the videos, (did no download the online applications as I don’t play online), as well last night after that message. If you’ve followed the above steps and are still having issues running Tiberian Sun on Windows 7, please post in the comments below. To increase your chances of a solution being found include as much detail as possible (which version of the game you’re running, what operating system you have, what video card you have and steps to reproduce the issue). Screenshots are also very useful! See the Westwood online support library is missing or invalid post for details on how to fix your internet components installation. Westwood online support library is missing or invalid. This error is caused by issues with your Westwood internet components installation or registeration.See the Tiberian Sun Failed to initialize post for details on how to resolve these compatibility issues. Please reinstall. This issue is related to compatibility issues with newer operating systems. See the Tiberian Sun DLL files missing or damaged post for details on how to fix your installation. Please reinstall.This issue is related to improper installation of Tiberian Sun. One or more DLL files were missing or damaged.See these posts on the respective issues for solutions to some of the common problems you may encounter: There are a few other issues you may run into when installing/playing the game. Start the game from the Game.exe. If you’re running the game from a shortcut instead, make sure the shortcut points to this file and is being run as administrator with Windows 98 compatibility.Make sure you do this for both of these files. Right click on your game.exe and SUN.exe files in your SUN directory, then go to compatibility and select run as administrator and run with Windows 98 compatibility. Set ALL game executables to run as Admin with Windows 98 compatibility mode.You can simply move your extracted EA Games folder to C:\Program Files\ if it isn’t there already. If you don’t have the game installed in this directory the included shortcuts and registry patch will not work. Your full game path should be as follows:Ĭ:\Program Files\EA Games\Command 6/30/2023 0 Comments Youtube moments in loveWhile humans may let us down, music never disappoints. And at the tail end of last year, Kendrick Lamar released the music video for “LOVE.”, redefining the word for all of mankind.Īnd still, many of us remain skeptical on this notion of true love. And let’s not forget about Frank Ocean, who brought the phrase “Thinking Bout You” to a whole nother level. “Yo” had guys sweeping their female crushes off their feet from across the room. Fast forward a couple decades, and Usher single-handedly takes over the R&B baby-making genre as a whole at least until Chris Brown comes along. It goes all the way back to the classics-after all, Marvin Gaye’s "Let's Get It On" remains one of the sexiest songs ever invented. The slow jams are inevitable, but sometimes, you just want to kick things up a notch. Whether you’re lighting candles to set the mood, cuddling up for warmth, or ready to make some babies, there’s only one thing left to do: put on the most romantic playlist known to mankind. The options for your perfect soundtrack are endless. With society’s ever-changing fads, trends, and fashions, one thing remains constant: love. Whether you have a boo, you’re looking for a boo, or you have several boos, you can always rely on that one record to take you back to a special time and place-that moment in your life that will never be forgotten-or to help you make new memories with a special someone. In the world of hip hop and R&B, cuffing season is all-year round, and the genres provide the perfect soundtrack to any love affair. There is a scene with a waterfall that is just breathtaking. With each film, the technical achievement Pixar is able to put on display is awe inspiring. The animation and artistry on display in Brave is second to none. Even more shocking Brave did not have a villain. In short the main conflict in the movie was quite dull. Instead it focused on a common and boring theme of an over controlling mother versus a rebellious daughter without anything creative or new to add to conversation. All we knew is she wanted her freedom, but for what end? So she could go horseback riding whenever she chose? Merida needed a purpose greater than herself and the movie never bothered to offer that. Merida’s character was very shallow and that really hurt the film. I really wished perhaps the story could have been about him. The only engaging character of the bunch was King Fergus. In fact if they had removed the odd bear subplot the story would have been much stronger for it.Įven worse, where Pixar films in the past were famous for their deep and meaningful characters, Brave was devoid of memorable heroes or villains. The sad part was the big plot twist was completely unneeded. The tone was not set as it switched stories completely midway through with an odd twist. The story seemed scattered and unfocused. The script, written by Chapman and Andrews with the help of rookie Steve Purcell and animation veteran Irene Mecchi (responsible for many of the weaker Disney animation films in the past two decades) did not help matters. By the time we come to the finale and the film finally slows down to show an emotional moment it is too late for it to have the kind of impact the movie needed. The movie races through emotional and tense moments where previous Pixar films would have taken it’s time. Many of the problems with Brave can be traced to the direction of this film. How these two earned a shot to direct a feature Pixar film I will never know, perhaps it’s magic. Andrews directed a previous Pixar short, One Man Band in addition to his screenplay credit on John Carter. Chapman’s last and only film was Prince of Egypt. The movie is directed by Brenda Chapman and Mark Andrews, neither of whom have stellar track records. In the end I couldn’t help thinking I had just seen a variation of a past Disney film Brother Bear. Brave seems to have all the right ingredients to fit among Pixar’s best but it never really comes together. While doing this many of them have a certain uniqueness about them whether it’s about a little robot seeking love or an elderly man befriending a pudgy boy scout on an adventure. They all hit just the right notes in terms of story and heart. Past Pixar movies have a certain magic to them. Now it is a race against time to reverse the curse before it destroys the kingdom and Merida’s family. The witch promises her a spell that can change her fate, but like all witch’s spells there are unintended consequences and things go horribly wrong. When Merida defies an age old custom of her people, picking her future husband from the surrounding kingdoms sons, Merida runs away into the forest and meets a witch. Merida is a tomboy at heart, much more happy to shoot arrows and mountain climb than to play princess, much to the dismay of her mother the Queen. 6/30/2023 0 Comments Magic bullet looks freeThis greatly benefits new users, too, as the Tool QuickDrawer lays out your tools by the process stages. Red Giant has done a great job with this interface, removing any mystery in what’s happening by adopting a graphical interface. Certain tools will correspond only to their relevant process stages, so a general understanding of color timing will help you achieve maximum effectiveness within the Tool Chain. The stages are Subject, Matte, Lens, Camera and Post. Below, you’ll find the new Tool Chain, which organizes your image adjustment tools into different stages to help you make better use of each tool. Both monitors are a necessity for understanding in general terms what you are doing to your image. To the right of the image, you can toggle on and off an RGB Parade monitor or a Slice Graph monitor. Looks chooses the still from where our playhead rests in Premiere Pro (you can change this in the Preferences). But the LooksBuilder will allow beginners to tinker and learn how to apply these effects with a straightforward building-block approach.Īt the launch of LooksBuilder, a still frame of our video clip is at the top left position. We don’t want to fool you, however, as the practice of color timing and its theory are not at all elementary. It might sound complicated, but it’s far from intimidating, as the LooksBuilder has a new graphical interface that’s incredibly simple to use. By “Looks,” we mean the grouping of different image adjustments and effects that you tweak within the LooksBuilder to create the final look of that image or video clip. The LooksBuilder is the main software interface for manipulating your different Looks. One drag, one drop and soon we’re launching the LooksBuilder application from the Effects tab in Premiere Pro. We chose to make some outdoor action-sports footage get a Looks makeover. Just like any other effects plug-in, Magic Bullet Looks installs the Looks effect as well as a myriad of Magic Bullet MisFire effects (i.e., dust, scratches and other film effects) into the effects library of your editing software. A few minutes later, we felt confident that this latest version would be much easier to navigate than previous versions. We chose to install Looks in Premiere Pro CS3 on our HP xw4600 workstation (2.66GHz Intel Core 2 Quad processor, 2GB RAM, NVIDIA Quadro FX1700 with 512MB video memory). We quickly checked the Help documentation before setting off on our journey. Magic Bullet Looks is available to both Mac and PC users, and it works with Apple Final Cut Pro and Motion 3, Avid Xpress and Media Composer and Adobe After Effects and Premiere Pro (be sure to check the technical specifications to see which versions apply). Throughout our tests, we saw no hiccups that would suggest that an update would chase this initial 1.0.0.0 release. Our installation took just a couple of minutes, and there were no updates at the time. The demo will add a red X watermark across your images as a result, but it’s fully functional and, like any effects software package, it’s extremely fun to play with for hours and hours. You can get your hands on the demo version right away with a 54MB download from Red Giant Software’s website. And, for most of us, it won’t require too much time reading how to do it. If you want to give your video a certain mood or motif or simply make it jump off the screen like never before, Magic Bullet Looks can get you there. Red Giant Magic Bullet Looks is a great jump forward in ease of use and still delivers stunning new looks for your digital video. 6/30/2023 0 Comments Pokemon x element chartGrass-type is Super Effective against Ground, Rock and Water-type.Grass-type is not very effective against Bug, Dragon, Fire, Flying, Grass, Poison and Steel-type.Grass-type resists Electric, Grass, Ground and Water-type.Grass-type is weak to Bug, Fire, Flying, Ice and Poison-type.Ghost-type Pokémon in Pokémon Let’s Go, Pikachu! and Pokémon Let’s Go, Eevee:Īlolan Marowak, Gastly, Gengar, Haunter and Mega Gengar. Ghost-type is Super Effective against Ghost and Psychic-type.Ghost-type is not very effective against Dark-type.Ghost-type is immune to Fighting and Normal-type.Ghost-type is weak to Dark and Ghost-type.Flying-type is Super Effective against Bug, Fairy, Fighting and Grass-typeįlying-type Pokémon in Pokémon Let’s Go, Pikachu! and Pokémon Let’s Go, Eevee:Īerodactyl, Articuno, Butterfree, Charizard, Dodrio, Doduo, Dragonite, Farfetch’d, Fearow, Golbat, Gyarados, Mega Aerodactyl, Mega Charizard X, Mega Charizard Y, Mega Gyarados, Mega Pidgeot, Mega Pinsir, Moltres, Pidgeot, Pidgeotto, Pidgey, Scyther, Spearow, Zapdos and Zubat.Flying-type is not very effective against Electric, Rock and Steel-type.Flying-type resists Bug, Fighting and Grass-type.Flying-type is weak to Electric, Ice and Rock-type.Fire-type is Super Effective against Bug, Grass, Ice and Steel-typeįire-type Pokémon in Pokémon Let’s Go, Pikachu! and Pokémon Let’s Go, Eevee:Īlolan Marowak, Arcanine, Charizard, Charmander, Charmeleon, Flareon, Growlithe, Magmar, Mega Charizard X, Mega Charizard Y, Moltres, Ninetales, Ponyta, Rapidash and Vulpix.Fire-type is not very effective against Dragon, Fire, Rock and Water-type.Fire-type resists Bug, Fairy, Fire, Grass, Ice and Steel-type.Fire-type is weak to Ground, Rock and Water-type.Hitmonchan, Hitmonlee, Machamp, Machoke, Machop, Mankey, Poliwrath, Primeape and Mega Mewtwo X. Fighting-type is Super Effective against Dark, Ice, Normal, Rock and Steel-typeįighting-type Pokémon in Pokémon Let’s Go, Pikachu! and Pokémon Let’s Go, Eevee:.Fighting-type is not very effective Bug, Flying and Poison-type.Fighting-type resists Bug, Dark and Rock-type.Fighting-type is weak to Fairy, Flying and Psychic-type. Fairy-type is Super Effective against Dark, Dragon and Fighting-typeįairy-type Pokémon in Pokémon Let’s Go, Pikachu! and Pokémon Let’s Go, Eevee:Īlolan Ninetales, Clefable, Clefairy, Jigglypuff, Mr.Fairy-type is not very effective against Fire, Poison and Steel-type.Fairy-type resists Dark and Fighting-type.Fairy-type is weak to Poison and Steel-type.Electric-type is Super Effective against Flying and Water-typeĮlectric-type Pokémon in Pokémon Let’s Go, Pikachu! and Pokémon Let’s Go, Eevee:Īlolan Geodude, Alolan Golem, Alolan Graveler, Alolan Raichu, Electabuzz, Electrode, Jolteon, Magnemite, Magneton, Pikachu, Raichu, Voltorb and Zapdos.Electric-type is not very effective against Dragon, Electric and Grass-type.Electric-type resists Electric, Flying and Steel-type.Dragon-type is Super Effective against Dragon-typeĭragon-type Pokemon in Pokémon Let’s Go, Pikachu! and Pokémon Let’s Go, Eevee:Īlolan Exeggutor, Dragonair, Dragonite, Dratini and Mega Charizard X.Dragon-type is not very effective against Steel-type.Dragon-type resists Electric, Fire, Grass, Water-type.Dragon-type is weak to Dragon, Fairy and Ice-type.Dark-type is Super Effective against Ghost and Psychic-typeĭark-type Pokemon in Pokémon Let’s Go, Pikachu! and Pokémon Let’s Go, Eevee:Īlolan Grimer, Alolan Meowth, Alolan Muk, Alolan Persian, Alolan Raticate, Alolan Rattata and Mega Gyarados.Dark-type is not very effective against Dark, Fairy and Fighting-type.Dark-type is weak to Bug, Fairy and Fighting-type.If a Pokemon attack type is listed as No Effect Against, its attacks will deal no damage to the specified Pokemon type.Bug-type Pokémon in Pokémon Let’s Go, Pikachu! and Pokémon Let’s Go, Eevee:īeedrill, Butterfree, Caterpie, Kakuna, Mega Beedrill, Mega Pinsir, Metapod, Paras, Parasect, Pinsir, Scyther, Venomoth, Venonat and Weedle. If a Pokemon attack type is listed as Weak Attack Against, its attacks will only deal half damage to the specified Pokemon type. O F F E N S E - If a Pokemon attack type is listed as Strong Attack Against, its attacks will deal double damage to the specified Pokemon type. If a Pokemon type is listed as Weak Defense Against, the Pokemon will sustain double damage from attacks of that type. If a Pokemon type is listed as Strong Defense Against, the Pokemon will only take half damage from attacks of that type. D E F E N S E - If a Pokemon type is listed as Immune against, it will take no damage from attacks of that type. 6/30/2023 0 Comments Prometheus node exporter helmKubectl -namespace default port-forward $POD_NAME 9091įor more information on running Prometheus, visit: Īt this point, you’ve successfully configured Prometheus to remote_write scraped metrics to Grafana Cloud. Get the PushGateway URL by running these commands in the same shell:Įxport POD_NAME=$(kubectl get pods -namespace default -l "app=prometheus,component=pushgateway" -o jsonpath="") The Prometheus server can be accessed via port 80 on the following DNS name from within your cluster: You can get a list of installed releases using helm list.Īfter running helm upgrade, you should see the following output: Release "" has been upgraded. Replace with the name of the release you used to install Prometheus. Upgrade the Prometheus Helm chart with the values file you just created using helm upgrade -f: helm upgrade -f new_values.yml prometheus-community/prometheus Now that you’ve created a values file with your Prometheus remote_write configuration, you can move on to upgrading the Prometheus Helm chart. When you’re done editing the file, save and close it. To learn how to create a Grafana Cloud API key, see Create a Grafana Cloud API key Your password corresponds to an API key that you can generate by clicking Generate now in the same panel. You can find your username by navigating to your stack in the Cloud Portal and clicking Details next to the Prometheus panel. Set the remote_write URL and basic_auth username and password using your Grafana Cloud credentials. Open a file named new_values.yaml in an editor and paste in the following values: server: You’ll first create a values file defining Prometheus’s remote_write configuration, and then you’ll apply this new configuration to the Prometheus deployment running in our cluster. To see the default values file for the Prometheus Helm chart, refer to values.yaml from the Prometheus Helm chart GitHub repository. With a Helm values file, you can set configuration variables that are passed in to Helm’s object templates. In this step, you’ll create a Helm values file to define parameters for Prometheus’s remote_write configuration. Create a Helm values file containing the remote_write configuration If you did not use Helm to install Prometheus into your cluster or are using Prometheus Operator and the kube-prometheus stack, select a different method. To learn how to install the Prometheus chart, see Install Chart from the Prometheus chart GitHub repo. To learn how to install Helm on your local machine, see Install Helm from the Helm documentation. This guide assumes you have installed the Prometheus Helm chart in your Kubernetes cluster using the Helm package manager. To learn more, see the Prometheus Helm chart GitHub repo. The Prometheus Helm chart provides a more lightweight foundation to build from than kube-prometheus-stack and can be useful if you don’t want to use Prometheus Operator or run a local Grafana instance. It configures a default set of Kubernetes observability scraping jobs for Prometheus. It also sets up kube-state-metrics, Pushgateway, Alertmanager, and node-exporter. The Prometheus Helm chart installs and bootstraps a one-replica Prometheus Deployment into your Kubernetes cluster. In this guide, you’ll learn how to configure Prometheus’s remote_write feature with Helm to ship cluster metrics to Grafana Cloud using Helm. Grafana Cloud Configure remote_write with Helm and Prometheus |